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DNA Synthesis Technologies | Industry Analysis | Market Size |

  • With an increased focus on automating DNA synthesis technologies, several developers have incorporated robust automatic techniques that enable the engineering of biological systems and study genome in a high throughput manner. This further leads to an increase in the yield of high-fidelity DNA fragments for use across several drug discovery and drug development processes.

    DNA synthesis has demonstrated to play a vital role in molecular and synthetic biology; various DNA synthesis technologies facilitate the use of DNA across several applications, including genetic engineering, and clinical diagnosis / treatment.

    With growing applications of DNA in medical research, industry stakeholders are actively looking for technologies that not only facilitate parallelized synthesis of DNA but also provide unmatched precision, scalability, and speed. The DNA synthesis services market is anticipated to grow at an annualized rate of more than 15% by 2035.

    The report features report features a detailed study of the current scenario and future potential of the DNA synthesis technologies and service providers. Further, the study underlines an in-depth analysis, highlighting the capabilities of service providers engaged in this domain. In addition to other elements, the study includes:

    • A detailed assessment of the overall landscape of the DNA synthesis technologies and services markets.
    • Elaborate profiles of the key players involved in providing technologies and services in the DNA synthesis domain.
    • A detailed overview of the current market landscape of oligonucleotide manufacturers focused on research and diagnostic applications, based on several relevant parameters.
    • A detailed overview of the current market landscape of oligonucleotide manufacturers focused on therapeutic applications, based on several relevant parameters.
    • An analysis of the partnerships established between various stakeholders in this domain, during the period 2017–2022.
    • A review of the funding and investments made in the domain, in the period between 2017 and 2022.
    • An in-depth analysis of grants that have been awarded to various research institutes for projects related to DNA synthesis technologies and services.
    • A detailed review of more than 12,000 peer-reviewed, scientific articles related to research on DNA synthesis technologies.
    • An in-depth analysis of the patents related to DNA synthesis technologies, filed / granted till 2022.
    • A detailed market forecast, featuring analysis of the current and projected future opportunity across key market segments (listed below).

    Method of DNA Synthesis

    • Chemical Method
    • Enzymatic Method

    Key Application Area(s)

    • Research and Diagnostics
    • Therapeutics

    Company Size

    • Small
    • Mid-sized
    • Large

    Key Geographical Region

    • North America
    • Europe
    • Asia-Pacific and the Rest of the World

    Key Companies Covered In The Report:

    • Ajinomoto Bio-Pharma Services
    • ATUM
    • DNA Script
    • Eurofins Genomics
    • Gene Universal
    • GenScript
    • Synbio Technologies

    Key Market Insights

    • Around 65 companies presently claim to have the required expertise for DNA synthesis technologies and affiliated services; of these, more than 50% players are small companies and have recently been established.
    • These technology and service providers claim to employ different cost-effective methods for the synthesis of DNA, having applications in various biomedical fields
    • There has been a notable increase in the published scientific literature related to DNA synthesis technologies and services in the last few years; such articles have been published in over 50 countries.
    • The growing interest in DNA synthesis technologies and services is reflected by the increase in partnership activity in the recent past; in fact, between 2019 and 2021, the partnership activity increased at a CAGR of 18%.
    • Over the past few years, 150 academic grants have been awarded to various organizations to support the ongoing efforts related to research and innovation in the field of DNA synthesis technologies.
    • Several investors, having realized the future opportunity associated with DNA synthesis technologies and services market, have invested more than USD 750 million in the past five years.
    • More than 11,000 patents have been filed / granted related to DNA synthesis technologies since 2016, establishing a strong portfolio of intellectual property within this industry.

    Financial Opportunity On This Domain

    Type of DNA Synthesis Method

    • Chemical Method
    • Enzymatic Method

    Key Application Areas

    • Research and Diagnostics
    • Therapeutic Applications

    Key Geographical Regions

    • North America
    • Europe
    • Asia Pacific and Rest of the World

    Key Inclusions

    • A detailed assessment of the overall landscape of the DNA synthesis technologies and services market, providing information on type of offering, method of DNA synthesis (chemical method and enzymatic method), type of DNA molecule, custom offerings, and application area. Additionally, the report provides information on drug developer(s) involved in the domain, along with analyses based on several relevant parameters, such as year of establishment, company size and geographical location of headquarters.
    • Elaborate profiles of the key players involved in providing technologies and services in the DNA synthesis domain. Each profile features a brief overview of the company, its financial information, details on its technology / service portfolio, financial information, and recent developments and an informed outlook.
    • A detailed overview of the current market landscape of oligonucleotide manufacturers focused on research and diagnostic applications, based on several relevant parameters, such as year of establishment, company size, scale of operation (preclinical, clinical, and commercial), location of headquarters, number of manufacturing facilities, along with information on the location of facility (country-wise), regulatory accreditations and certifications received, type of oligonucleotide manufactured (antisense oligonucleotides, aptamers, decoys, miRNA, shRNA, siRNA, specialty amidites and others), type of offering (custom synthesis, modification and purification), type of manufacturing service(s) offered (process development and characterization, method validation and testing, analytical development, sequencing capabilities, stability studies, quality assurance and control, fill / finish, regulatory support, data analytics and reporting, and others) and type of modification(s) offered (amino modifiers, backbone modifications, fluorescent probes, dyes and quenchers, modified bases, phosphorylation, thiol modifications and others).
    • A detailed overview of the current market landscape of oligonucleotide manufacturers focused on therapeutic applications, based on several relevant parameters, such as year of establishment, company size, scale of operation (preclinical, clinical, and commercial), location of headquarters, number of manufacturing facilities, along with information on the location of facility (country-wise), regulatory accreditations and certifications received, type of oligonucleotide manufactured (antisense oligonucleotides, aptamers, decoys, miRNA, shRNA, siRNA, specialty amidites and others), type of offering (custom synthesis, modification and purification), type of manufacturing service(s) offered (process development and characterization, method validation and testing, analytical development, sequencing capabilities, stability studies, quality assurance and control, fill / finish, regulatory support, data analytics and reporting, and others) and type of modification(s) (amino modifiers, backbone modifications, fluorescent probes, dyes and quenchers, modified bases, phosphorylation, thiol modifications and others).
    • An analysis of the partnerships established between various stakeholders in this domain, during the period 2017–2022, covering product development and commercialization agreements, R&D agreements, technology licensing agreements, other licensing agreements, mergers and acquisitions, and other relevant types of deals.
    • A review of the funding and investments made in the domain, in the period between 2017 and 2022, including seed financing, venture capital financing, debt financing, grants, capital raised from IPOs and subsequent offerings, at various stages of development. The analysis has been done based on several parameters, such as number of funding instances, amount invested, type of funding, leading players and investors, and geographical analysis.
    • An in-depth analysis of grants that have been awarded to various research institutes for projects related to DNA synthesis technologies and services, in the period between 2017 and 2022, on the basis of important parameters, such as year of grant award, grant amount awarded, administering institute center, support period, type of grant application, grant activity code, emerging focus area, purpose of grant award, type of recent organization, popular NIH department and prominent program officers.
    • A detailed review of more than 12,000 peer-reviewed, scientific articles related to research on DNA synthesis technologies, which have been published between 2017 and 2022, including analysis based on parameters, such as year of publication, key focus area, type of article, popular keywords, popular authors, therapeutic area, geography, and key journals (in terms of number of articles published in this domain and impact factor of the journal).
    • An in-depth analysis of the patents related to DNA synthesis technologies, filed / granted till 2022, based on various parameters, such as patent publication year, geographical location / patent jurisdiction, CPC symbols, emerging focus areas, and type of applicant, and leading players (by number of patents). In addition, it features a patent valuation analysis which evaluates the qualitative and quantitative aspects of the patents.

    Key Questions Answered

    1. Who are the leading industry players offering DNA synthesis technologies and services?
    2. What are the recent developments and emerging trends in the DNA synthesis technologies and services domain?
    3. Which partnership models are commonly adopted by industry stakeholders in the DNA synthesis technologies and services industry?
    4. Which are the leading funding organizations providing grants in the DNA synthesis industry?
    5. What is the trend of capital investments in the DNA synthesis technologies and services market?
    6. What is the focus of various publications related to DNA synthesis technologies and services?
    7. How has the intellectual property landscape for DNA synthesis technologies and services market evolved over the years?
    8. Which factors are likely to influence the evolution of the upcoming DNA synthesis technologies and services market?
    9. How is the current and future opportunity likely to be distributed across key market segments?